Recurrent intestinal perforations as a presentation of antiphospholipid syndrome.

نویسندگان

  • Saleh Al-Daqal
  • Majed Mansouri
  • Mohammed H Qari
  • Abdulrahman Sibiany
چکیده

Ann Saudi Med 2006;26(1):52-55 Antiphospholipid syndrome (APS) is a rare but important cause of thrombosis. It is suspected in patients who present with recurrent thrombosis or thrombosis in an unusual site. Gastrointestinal involvement is rare in this syndrome. Moreover, intestinal perforation in APS is very rare. We report a 19-year-old female patient who developed recurrent spontaneous intestinal perforations in which repeated laparotomies were undertaken and different diagnoses were entertained. The patient had received different treatments but without improvement. Antiphospholipid syndrome (APS) was suspected and diagnosed, and subsequently anticoagulant therapy was started. To our knowledge, this is a first report describing recurrent small intestinal perforation in a patient with APS.

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Antiphospholipid syndrome is an autoimmune condition characterized by recurrent vascular thrombosis, pregnancy loss and thrombocytopenia associated with moderate to high levels of antiphospholipid antibodies. Most of clinical features are results of thrombotic phenomena. The pathophysiologic basis ot this syndrome is still unknown. the diagnosis of this syndrome is made by combination of clinic...

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عنوان ژورنال:
  • Annals of Saudi medicine

دوره 26 1  شماره 

صفحات  -

تاریخ انتشار 2006